Mildronate Meldonium 40 capsules /250 mg each

Mildronat - preparation, improves metabolism and energy supply of tissues.

40 capsules  ,250 mg  meldoniun in each  capsules.

USES
Improves Oxygen Delivery to Cells
Excellent for Sportsmen to Improve Stamina
Protects Cells from Intoxication
Improves Energy Levels and Faster Physical Recovery
Treat Chronic Heart Failure and Cerebral Strokes
Abstinence Syndrome

Release form and composition

Mildronat available in the following dosage forms:

Capsules: white hard gelatin 250 mg; contents of capsules - hygroscopic crystalline white powder with a weak odor (in blister packs of 10 pieces 6 blisters in a carton box.);

The structure of 1 capsule contains:

Active ingredient: meldonium dihydrate -  250 mg;

Auxiliary ingredients: potato starch - 13.6 / 27.2 mg; Colloidal silicon dioxide - 5.4 / 10.8 mg; calcium stearate - 2.7 / 5.4 mg.

The composition of the capsule shell: E171 (titanium dioxide) - 2%; Gelatin - 100%.

Indications

• Reduced working capacity, physical stress (including the athletes);
• abstinence syndrome in chronic alcoholism (both with specific alcoholism therapy);
• Coronary heart disease (myocardial infarction, angina), congestive heart failure (as a part of complex treatment);
• Acute and chronic cerebral circulatory disorders, including stroke and cerebrovascular insufficiency (in the complex treatment).

In addition to Mildronate in the form of a solution for injection:

• Thrombosis of central retinal vein and its branches;
• Hemophthalmus, retinal hemorrhages of different etiologies;
• Retinopathy of different etiology (hypertensive, diabetic).

Contraindications

• Increased intracranial pressure (including intracranial tumors, venous outflow violation);
• Hypersensitivity to the drug.

Prescribe drugs to children under 18 years of age and lactating and pregnant women is not recommended due to a lack of clinical evidence supporting the safety and efficacy of Mildronate these groups of patients.

Mildronat should be used with caution in patients with kidney and / or liver disease (especially long-term).

Dosage and Administration

Due to the possible development of stimulating effect Mildronat recommended in the first half of the day, while taking a few times a day - no later than 17.00.

Inside Mildronat in capsule form is usually prescribed as follows:

• Coronary heart disease (myocardial infarction, angina), congestive heart failure: a daily dose - 500-1000 mg; the multiplicity of reception - 1-2 times a day. The duration of the therapeutic course - 1-1.5 months (along with other drugs);
• Dishormonal cardiomyopathy: daily dose - 500 mg. The duration of the therapeutic course - 12 days (in conjunction with other drugs);
• Subacute cerebrovascular accident (stroke and cerebrovascular insufficiency): daily dose - 500-1000 mg; the multiplicity of reception - 1-2 times a day. The duration of the therapeutic course - 1-1.5 months (the drug is taken orally in conjunction with other drugs after the end of injection therapy Mildronate);
• Chronic disorders of cerebral circulation: daily dose - 500 mg. The duration of the therapeutic course - 1-1.5 months (along with other drugs). Perhaps repeat courses (usually 2-3 times a year) after a medical consultation;
• Decreased performance, mental and physical stress (including the athletes): daily dose - 1000 mg; the multiplicity of reception - 2 times a day. The duration of the therapeutic course - 10-14 days. After 2-3 weeks, possible to carry out repeated course;
• Abstinence syndrome in chronic alcoholism: daily dose - 2000 mg; multiplicity of reception - 4 times a day. The duration of the therapeutic course - 7-10 days (at the same time to the specific treatment of alcoholism).

Competitors are advised to take before workouts Mildronat a single dose of 500-1000 mg 2 times a day. The duration of the preparatory period - 2-3 weeks, during the period of competition - 10-14 days.

Mildronat in the form of a solution for injection is administered intravenously and parabulbarno.

Typically, the drug is prescribed intravenously:

• Cardiovascular disease: daily dose - 500-1000 mg (5-10 ml solution for injection, the concentration - 500 mg / 5 ml); the multiplicity of application 1-2 times a day. Duration of course of treatment - 1-1,5 months (along with other drugs);
• Violations of cerebral circulation (acute phase): daily dose - 500 mg; the multiplicity of application - 1 time per day. Solution was administered for 10 days and then transferred to the reception Mildronate inside (500-1000 mg per day). The total duration of the course of treatment - 1-1,5 months;
• Physical and mental stress: daily dose - 500 mg; the multiplicity of application - 1 time per day. The duration of the treatment course - 10-14 days. After 2-3 weeks, possible to carry out repeated course;
• Alcoholism: daily dose - 1000 mg; multiplicity of application - 2 times a day. The duration of the treatment course - 10-14 days.

In vascular pathologies and degenerative diseases of the retina Mildronat parabulbarno should be administered at a dose of 0.5 ml solution for injection at a concentration of 500 mg / 5 ml for 10 days.

Side effects

In rare cases, when applying Mildronate in all dosage forms may develop side effects such as: allergic reaction (itching, redness of the skin, hives, skin rash, angioedema), dyspepsia, tachycardia, increased or decreased blood pressure, increased excitability.

In very rare cases may develop eosinophilia and total weakness.