PresentationSolution for oral and rectal administration in 20 ml or 100 ml vials. Four or ten 20 ml vials or one 100 ml vial in each cardboard package with a package insert.
IngredientsThe preparation is a mixture of sterile filtrates of phage lysates of Shigellaflexneri 1, 2, 3, 4, 6 serovariants, Shigellasonnei, SalmonellaparatyphiA, SalmonellaparatyphiB, Salmonellatyphimurium, Salmonellainfantis, Salmonellacholeraesuis,
Salmonellaoranienburg, Salmonellaenteritidis, enteropathogenic Escherichiacoli of various serogroups which play a key role in the ethiology of enteral deseases, Proteusvulgaris, Proteusmirabilis, Enterococcus, Staphylococcus, Pseudomonasaeruginosa.
Preservative - 8-hydroxyquinoline sulfate monohydrate - 0.0001 g/ml (estimated content);
or 8-hydroxyquinoline sulfate monohydrate - 0.0001 g/ml (equal to 8-hydroxyquinoline sulfate).
Treatment and prevention of diseases of the gastrointestinal tract caused by bacteria of dysentery, Salmonella, Escherichia coli, Proteus, enterococci, staphylococci, Pseudomonas aeruginoza or a combination thereof.
- bacterial dysentery;
- enterocolitis, colitis.
An important condition for the effective phage therapy is a preliminary determination of the phage sensitivity of the pathogen.
Dosage regimen and method of application
The drug is intended for oral administration and rectal administration. For treatment, the drug is taken orally 4 times a day for 0.5 - 1 hour before meals from the first day of the disease for 7-10 days.
For children in the first months of life, the drug is diluted twice with boiled water in the first two days of administration, in the absence of adverse reactions (regurgitation, rashes on the skin) in the future, you can use undiluted bacteriophage. The drug is administered by mouth 3 times a day 30 minutes before feeding. In cases of indomitable vomiting, the drug is used in the form of high enemas (through a gas tube or catheter) daily. A combination of rectal (in the form of high enemas) and oral administration of the drug is possible. The course of treatment is 7 to 10 days.
Age Dose at 1 dose (ml)
0 - 6 months 5 10
6 - 12 months 10-15 20
from 1 year to 3 years 15-20 20-30
from 3 to 8 years 20-30 30-40
from 8 years and older 30-40 50-60
In the absence of colitic syndrome, it is recommended to replace one ingestion with a single rectal administration of a single age-related dose in the form of an enema after bowel movement.
For preventive purposes, the optimal regimen is a daily dose of a single age-related dose. The duration of the drug is determined by the conditions of the epidemiological situation.