Polyoxidonium lyophilizate for solution for injections and topical application 6 mg in each bottle
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PHARMACOLOGICAL PROPERTIES
Polyoxidonium® tablets possesses an immune modulating action, increases the organism
resistance to local and general infections. Polyoxidonium’ main mechanism of action is the direct
effect on the phagocytic cells and natural killers together with antibody production stimulation.
Polyoxidonium®
recovers the immunity in different secondary deficiencies caused by
different infections, traumas, burns, malignant neoplasm, post-surgical complications,
chemotherapy, cytostatics, and steroid hormones.
Together with the immune modulating properties Polyoxidonium®
possesses an expressed
detoxicating and antioxidant properties; is able to eliminate toxins, heavy metals ions from the
organism, and inhibits the lipid peroxidation. All propertied mentioned are determined by
Polyoxidonium structure and high molecular nature.
Polyoxidonium®
inclusion into the
chemotherapy of oncologic patients results in therapy-induced intoxication alleviation, and allows
to perform complete standard chemo- or radiotherapy cycle without infection complications and
side effects (myelosuppression, vomiting, diarrhea, cystitis, colitis etc.) that are often the reason
for therapy preterm termination.
Polyoxidonium application for secondary immune deficiencies allows to increase therapy
efficacy and to shorten its duration, significantly to reduce the antibiotics, broncholitics,
clucocorticoids application, and to lengthen the remission period.
The preparation is well tolerated, has no mitogenic, polyclonal activity, free from antigen
properties, and has no allergenic, mutagenic, embryo toxic, teratogenic and carcinogenic potential.
