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LAFEROBION® suppositories 10 in pack antiviral, antiproliferative and immunomodulating effect

LAFEROBION® suppositories 10 in pack  antiviral, antiproliferative and immunomodulating effect
Product Code :924
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Laferobion - suppositories 10 in pack . One pack




Packaging  -10 suppositories in a blister pack. 1 blister pack with 2 blister packs with 5 suppositories in a cardboard box

 

Composition 1 suppository contains: interferon alpha-2b recombinant human — 150,000 IU or 500,000 IU

 

Age  Children from the very birth

 

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LAFEROBION® suppositories 150,000 MO, suppositories 500,000 MO

 

INSTRUCTION

for medical use of the drug

LAFEROBION®

LAFEROBIONUM®

Composition:

active substance: interferon alfa-2b

 

1 suppository contains: recombinant human interferon alfa-2b - 150,000 IU or 500,000 IU;

 

excipients: tocopherol acetate 5% butyric solution, ascorbic acid, solid fat.

 

Dosage form.

Suppositories.

 

The main physico-chemical properties: suppositories bullet-shaped yellowish-white color with a homogeneous consistency.

 

Pharmacotherapeutic group.

Immunostimulants. Interferons. Interferon alfa-2b.

 

ATX code L03A B05.

 

Pharmacological properties.

Pharmacodynamics

antiviral, antiproliferative and immunomodulating effect.

Interferon alfa-2b recombinant has a pronounced antiviral, antiproliferative and immunomodulating effect. The active substance of the drug Laferobion® - interferon alpha-2b recombinant has an immunomodulating effect on T and B lymphocytes, normalizes the content of immunoglobulin E, and has antiviral activity. Antibodies are not formed that neutralize the antiviral activity of recombinant interferon alpha-2b, even when used for 2 years, the functioning of the endogenous system is normalized.

 

Pharmacokinetics

 

The pharmacokinetic properties of recombinant interferon alfa-2b have been little studied.

 

Clinical characteristics

Indications.

For children: in the complex treatment of acute respiratory viral infections (ARVI).

 

Contraindications

Hypersensitivity to the components of the drug; the patient has thyroid dysfunction; the presence of severe visceral disorders in patients with Kaposi's sarcoma; severe cardiovascular disease; psoriasis, severe impaired liver and / or kidney function; epilepsy and other diseases of the central nervous system (including functional); chronic hepatitis with progressive or decompensated liver cirrhosis; chronic hepatitis in patients receiving or recently receiving immunosuppressant therapy (except for a short course of corticosteroid therapy); a history of autoimmune hepatitis or other autoimmune diseases. Inhibition of the myeloid germ of hematopoiesis.

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